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Tec-Control Chromatography Systems

Biodex

Tec-Control Chromatography Systems


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For radiopharmaceutical quality control

Tec-Control Chromatography tests the radiochemical purity of specific Tc-99m-labeled radiopharmaceuticals. The accompanying chart shows which strips and solvents are required to perform each individual test. Some solvents must be purchased separately (see Sigma-Aldrich chart) due to hazardous material shipping restrictions.

Detailed instruction manuals are packaged with each strip container, although our Radiopharmaceutical QC Procedure Manual (151-000) explains paper chromatography in greater detail.

References:

Miniaturized Chromatographic Quality-Control Procedures for Tc-99m Radiopharmaceuticals; A. Michael Zimmer and Dan G. Pavel, Journal of Nuclear Medicine, Vol. 18/12, Dec. 1977, pg. 1230.

Technical Parameters Associated with Miniaturized Chromatography Systems; Raimund A. Taukulis, A. Michael Zimmer, Dan G. Pavel and Bhupendra A. Patel, University of Illinois Medical Center, Chicago, Illinois, Journal of Nuclear Medicine Technology, Vol. 7/1.

RADIOPHARMACEUTICAL  SOLVENT(S) REQUIRED*  STRIPS REQUIRED 
 Aluminum Breakthru  150-781 10 µg/ml  150-782  
 Aluminum Breakthru  150-783 5 µg/ml  150-782 
 Bicisate (Neurolite™)  Ethyl Acetate 99.%  150-130 
 Diphosphonate  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 Disofenin (Hepatolite™)  150-160, Distilled H2O  150-122 & 150-125 
 DMSA  Acetone (HPLC Grade),  150-025 
 DTPA  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 Exametazine (Ceretec™)  Ethyl Acetate 99.% 
150-130 
 Fluorodeoxyglucose (FDG)
Acetone (HPLC Grade) 150-127
 Glucoheptonate  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 HDP  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 MAA  Acetone (HPLC Grade),  150-001 
 MAG3 (Mertiatide™)  Acetone, (HPLC Grade),
Chloroform 99.8%
Tetrahydrofuran 99+% 
150-951 & 150-952 
 MDP  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 Mebrofenin (Cholotec™)  150-160, Distilled H2O  150-122 & 150-125 
 Pyrophosphate  Acetone (HPLC Grade), Distilled H2O  150-001 & 150-005 
 Sestamibi (Cardiolite™ and  
 Miraluma™) 
Ethyl Acetate 99.%  150-991 
 Sulphur Colloid  Acetone (HPLC Grade)  150-001 
 Tc-99m (reduced)  Acetone (HPLC Grade),  150-001  
 Tc-99m Monoclonal  Antibodies  0.9% Saline  150-771
 Tetrofosmin (Myoview™)  Ethyl Acetate 99.% 
150-971 
 In-111 Octreotide
 (Octreoscan™) 
150-773 & 0.9% Saline  150-771 **
 In-111 Monoclonal
 Antibodies 
150-773 & 0.9% Saline  150-771 ** 
 In-111/Y-90 Zevalin™  0.9% Saline  150-772 
 I-131 Monoclonal Antibodies
 And Neutrospec™ 
0.9% Saline  150-771 

* See Sigma-Aldrich product matrix for solvents.
** Note: A Well Plate is suggested to perform QC on these radiopharmaceuticals


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